By Helena J. Heuvelman M.D., Nalini Marie Rajamannan M.D. (auth.), Nalini M. Rajamannan (eds.)

The publication can be written through the specialists within the affliction together with imaging, interventional cardiology and surgical valve services. The publication has 5 major sections: Aortic Valve illness Mitral Valve illness Tricuspid Valve sickness Pulmonic Valve illness Multimodality Imaging the most ambitions of the booklet are: 1- to supply the most instructions to clinicians on tips to establish and diagnose valvular middle affliction 2- to supply an outline of what the close to destiny will herald the analysis, prevention and hazard stratification of sufferers to catheter as opposed to surgical techniques three- to stipulate the potential implications for scientific treatments in slowing development of calcific aortic valve disorder and myxomatous mitral valve disease

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5 The Electrocardiogram as a Risk Predictor in Asymptomatic Aortic Stenosis Anders M. Greve and Kristian Wachtell Calcific aortic stenosis (AS) shares several etiological factors and histopathological changes with vascular atherosclerosis and the two diseases often coincide (Otto et al. 1994). Observed cardiovascular event rates might therefore differ substantially despite equal AS severity in the presence of additional vascular disease, such as atherosclerosis or hypertension (Otto et al. 1999; Briand et al.

Nephron Clin Pract. 2003;93(4):c124–30. Verberckmoes SC, Persy V, Behets GJ, Neven E, Hufkens A, Zebger-Gong H, Muller D, Haffner D, Querfeld U, Bohic S, De Broe ME, D’Haese PC. Uremia-related vascular calcification: more than apatite deposition. Kidney Int. 2007;71(4):298–303. Wang AY-M, Woo J, Lam CW-K, Wang M, Chan IH-S, Gao P, Lui S-F, Li PK-T, Sanderson JE. Associations of serum fetuin-A with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients.

2011. 1007/s10237-012-0375-x Chandra S, Rajamannan NM, Sucosky P. Computational assessment of bicuspid aortic valve wall-shear stress: implications for calcific aortic valve disease. Biomech Model Mechanobiol. 2012. 1007/s10237-012-0375-x. Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D. Mutations in NOTCH1 cause aortic valve disease. Nature. 2005;437(7056):270–4. 3 Bicuspid Aortic Valve Disease: From Bench to Bedside Lee TC, Zhao YD, Courtman DW, Stewart DJ.

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